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Cofilin monoclonal antibody

货号: MB11974

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11974

Product Name :Cofilin monoclonal antibody

Swiss-Prot :P23528

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 19 kDa; Observed MW: 19 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform

Immunogen :A synthetic peptide of human Cofilin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Cofilin in A549, MCF-7, 293T lysates using Cofilin antibody.

Immunocytochemistry analysis of Cofilin in hela using Cofilin antibody,and DAPI