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Caspase 6 monoclonal antibody

货号: MB11949

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB11949

Product Name :Caspase 6 monoclonal antibody

Swiss-Prot :P55212

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 33 kDa; Observed MW: 11,33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

Immunogen :A synthetic peptide of human Caspase-6

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Caspase6 in A549, MCF-7, U251, HL-60 lysates using Caspase 6 antibody.

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Caspase6 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.