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Phospho-TrkB (Tyr705) monoclonal antibody

货号: MB11898

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11898

Product Name :Phospho-TrkB (Tyr705) monoclonal antibody

Swiss-Prot :Q16620

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 92 kDa; Observed MW: 140,90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr705 of human TrkB

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-TrkB in Hela, A549, C6 lysates using Phospho-TrkB antibody.