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Phospho-Smad1 (Ser463/Ser465) monoclonal antibody

货号: MB11894

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11894

Product Name :Phospho-Smad1 (Ser463/Ser465) monoclonal antibody

Swiss-Prot :Q15797

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 52 kDa; Observed MW: 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human Smad1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Smad1 in A549, U2OS, C6 lysates using Phospho-Smad1 antibody.