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Phospho-RSK1 p90 (Ser380) monoclonal antibody

货号: MB11893

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11893

Product Name :Phospho-RSK1 p90 (Ser380) monoclonal antibody

Swiss-Prot :Q15418

Host :Rabbit

Reactivity :Hamster,Mouse

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 83 kDa; Observed MW: 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser380 of human RSK1 p90

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of RSK1 p90 in CHO-K1 lysates using Phospho-RSK1 p90 antibody.