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Phospho-AKT1 (Thr450) monoclonal antibody

货号: MB11846

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11846

Product Name :Phospho-AKT1 (Thr450) monoclonal antibody

Swiss-Prot :P31749

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 56 kDa; Observed MW: 56 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr450 of human AKT1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-AKT1 in U2OS, C6 lysates using Phospho-AKT1 antibody.