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Notch4 monoclonal antibody

货号: MB11841

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11841

Product Name :Notch4 monoclonal antibody

Swiss-Prot :Q99466

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 210 kDa; Observed MW: 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4

Immunogen :A synthetic peptide of human NOTCH4

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NOTCH4 in Hela, U87-MG lysates using Notch4 antibody.

免疫沉淀（IP）