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Cadherin 5 monoclonal antibody

货号: MB11762

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11762

Product Name :Cadherin 5 monoclonal antibody

Swiss-Prot :P55284

Host :Rabbit

Reactivity :Mouse

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 88 kDa; Observed MW: 90-140 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225

Immunogen :Recombinant protein of mouse VE Cadherin

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of VE Cadherin in mouse lung lysates using Cadherin 5 antibody.

免疫沉淀（IP）