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U1C monoclonal antibody

货号: MB11742

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11742

Product Name :U1C monoclonal antibody

Swiss-Prot :P09234

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background :Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 17 kDa; Observed MW: 21 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C

Immunogen :A synthetic peptide of human U1-C

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of U1C in rat lung lysates using U1C antibody.

免疫沉淀（IP）