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Topoisomerase I monoclonal antibody

货号: MB11707

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11707

Product Name :Topoisomerase I monoclonal antibody

Swiss-Prot :P11387

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 91 kDa; Observed MW: 91 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TOP1; DNA topoisomerase 1; DNA topoisomerase I

Immunogen :A synthetic peptide of human Topoisomerase I

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Topoisomerase I in K562, rat Brain, C6, 3T3, Hela lysates using Topoisomerase I antibody.

Immunocytochemistry analysis of Topoisomerase I in Hela using Topoisomerase I antibody,and DAPI