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TIAM2 monoclonal antibody

货号: MB11693

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11693

Product Name :TIAM2 monoclonal antibody

Swiss-Prot :Q8IVF5

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane . Activates specifically RAC1, but not CDC42 and RHOA.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 190 kDa; Observed MW: 190 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :STEF; TIAM-2

Immunogen :Recombinant protein of human TIAM2

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of TIAM2 in K562, 293 lysates using TIAM2 antibody.

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