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Transcription Factor 7 Like 2 monoclonal antibody

货号: MB11678

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11678

Product Name :Transcription Factor 7 Like 2 monoclonal antibody

Swiss-Prot :Q9NQB0

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 68 kDa; Observed MW: 68 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TCF7L2; HMG box transcription factor 4; HTCF-4; T-cell factor-4 variant X2; T-cell factor 4; Transcription factor 7-like 2; TCF-4

Immunogen :A synthetic peptide of human TCF-4

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of TCF4 in K562, Hela lysates using Transcription Factor 7 Like 2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using TCF4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.