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Phospho-TAK1 (Ser439) monoclonal antibody

货号: MB11666

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11666

Product Name :Phospho-TAK1 (Ser439) monoclonal antibody

Swiss-Prot :O43318

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 67 kDa; Observed MW: 78 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser439 of human TAK1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of TAK1 in 3T3, C6, MCF-7 lysates using Phospho-TAK1 antibody.