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Smad5 monoclonal antibody

货号: MB11610

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11610

Product Name :Smad5 monoclonal antibody

Swiss-Prot :Q99717

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. Smad5 is a receptor-regulated Smad (R-Smad). Smad5 is required for normal development of the cardiovascular system in vivo; lack of the Smad5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of Smad5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 52 kDa; Observed MW: 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DKFZp781C1895; DKFZp781O1323; Dwfc; hSmad 5; hSmad5; JV5 1; JV5-1; MAD homolog 5; MAD mothers against decapentaplegic homolog 5; MAD; mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD mothers against DPP homolog 5; Smad5; Smad5; SMAD5_HUMAN.

Immunogen :A synthetic peptide of human SMAD5

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Smad5 in C6, Hela lysates using Smad5 antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using SMAD5 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.