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RALB monoclonal antibody

货号: MB11508

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11508

Product Name :RALB monoclonal antibody

Swiss-Prot :P11234

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles . Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells . Required for suppression of apoptosis (PubMed:17875936). In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 23 kDa; Observed MW: 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ras-related protein Ral-B

Immunogen :A synthetic peptide of human RALB

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of RALB in mouse colon lysates using RALB antibody.

免疫沉淀（IP）