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RAGE monoclonal antibody

货号: MB11506

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11506

Product Name :RAGE monoclonal antibody

Swiss-Prot :Q15109

Host :Rabbit

Reactivity :Mouse

Applications :WB

Application_all :WB: 1/500-1/1000

Background :The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily. Mediates interactions of advanced glycosylation end products (AGE). Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 43 kDa; Observed MW: 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products

Immunogen :A synthetic peptide of human RAGE

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of RAGE in mouse lung lysates using RAGE antibody.

Qifu-yin activates the Keap1/Nrf2/ARE signaling and ameliorates synaptic injury and oxidative stress in APP/PS1 mice

JournalJOURNAL OF ETHNOPHARMACOLOGY

ApplicationWB

IF4.8

SpeciesMouse

PMID38942156