产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Phospho-Raf1 (Ser259) monoclonal antibody

货号: MB11504

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11504

Product Name :Phospho-Raf1 (Ser259) monoclonal antibody

Swiss-Prot :P04049

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 73 kDa; Observed MW: 73 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser259 of human Raf1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-Raf1 in K562, C6, 3T3, Hela lysates using Phospho-Raf1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Raf1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.