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Rad51D monoclonal antibody

货号: MB11502

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11502

Product Name :Rad51D monoclonal antibody

Swiss-Prot :O75771

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 35 kDa; Observed MW: 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TRAD; R51H3; BROVCA4; RAD51L3

Immunogen :Recombinant protein of human Rad51D

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Rad51D in K562, C6, 3T3, Hela lysates using Rad51D antibody.

免疫沉淀（IP）