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PP2A alpha/beta monoclonal antibody

货号: MB11444

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11444

Product Name :PP2A alpha/beta monoclonal antibody

Swiss-Prot :P67775

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 36 kDa; Observed MW: 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C

Immunogen :A synthetic peptide of human PP2A alpha

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PP2A alpha/beta in K562, rat Brain, C6, 3T3 lysates using PP2A alpha/beta antibody.

免疫沉淀（IP）