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RNA Polymerases I/II/III Subunit ABC1 monoclonal antibody

货号: MB11439

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11439

Product Name :RNA Polymerases I/II/III Subunit ABC1 monoclonal antibody

Swiss-Prot :P19388

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process .

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 25 kDa; Observed MW: 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RPB5; XAP4; RPABC1; hRPB25; hsRPB5

Immunogen :A synthetic peptide of human POLR2E

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of POLR2E in K562, C6, 3T3, Hela lysates using RNA Polymerases I/II/III Subunit ABC1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using POLR2E antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.