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Phospho-PKR (Thr451) monoclonal antibody

货号: MB11432

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11432

Product Name :Phospho-PKR (Thr451) monoclonal antibody

Swiss-Prot :P19525

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1/500-1/1000

Background :PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 62 kDa; Observed MW: 74 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr451 of human PKR

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of PKR in Hela, Hela+CalyculinA lysates using Phospho-PKR antibody.