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PKN1 monoclonal antibody

货号: MB11431

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11431

Product Name :PKN1 monoclonal antibody

Swiss-Prot :Q16512

Host :Rabbit

Reactivity :Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 104 kDa; Observed MW: 120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA

Immunogen :A synthetic peptide of human PKN

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PKN in C6 lysates using PKN1 antibody.

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