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Phospho-p27 Kip 1 (Ser10) monoclonal antibody

货号: MB11350

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11350

Product Name :Phospho-p27 Kip 1 (Ser10) monoclonal antibody

Swiss-Prot :P46527

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 22 kDa; Observed MW: 27 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CDKN1B; KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser10 of human p27 KIP 1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-p27 KIP 1 in Hela, 3T3 lysates using Phospho-p27 Kip 1 antibody.

Western blot analysis of Phospho-p27 KIP 1 in C6 lysates using Phospho-p27 KIP 1 antibody.