产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

NUMB monoclonal antibody

货号: MB11334

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11334

Product Name :NUMB monoclonal antibody

Swiss-Prot :P49757

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 71 kDa; Observed MW: 71 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NUMB; Protein numb homolog; h-Numb; Protein S171

Immunogen :Recombinant protein of human NUMB

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NUMB in 3T3, C6, rat Brain, MCF-7 lysates using NUMB antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using NUMB antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.