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Notch1 monoclonal antibody

货号: MB11318

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB11318

Product Name :Notch1 monoclonal antibody

Swiss-Prot :P46531

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 273 kDa; Observed MW: 120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1

Immunogen :A synthetic peptide of human Notch1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Notch1 in C6, Hela lysates using Notch1 antibody.

免疫沉淀（IP）