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NOLC1 monoclonal antibody

货号: MB11317

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11317

Product Name :NOLC1 monoclonal antibody

Swiss-Prot :Q14978

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus (PubMed:9016786). It has intrinsic GTPase and ATPase activities (PubMed:9016786).

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 74 kDa; Observed MW: 110 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :P130; NOPP130; NOPP140; NS5ATP13

Immunogen :A synthetic peptide of human NOLC1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NOLC1 in Jurkat lysates using NOLC1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NOLC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.