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Nogo B Receptor monoclonal antibody

货号: MB11316

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB11316

Product Name :Nogo B Receptor monoclonal antibody

Swiss-Prot :Q96E22

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 33 kDa; Observed MW: 33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199

Immunogen :A synthetic peptide of human Nogo B receptor

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Nogo B receptor in K562, 3T3, Hela lysates using Nogo B Receptor antibody.

免疫沉淀（IP）