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Nesprin3 monoclonal antibody

货号: MB11295

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11295

Product Name :Nesprin3 monoclonal antibody

Swiss-Prot :Q6ZMZ3

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1/500-1/1000

Background :As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 112 kDa; Observed MW: 112 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341

Immunogen :Recombinant protein of human Nesprin3

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Nesprin3 in Jurkat, Hela lysates using Nesprin3 antibody.

免疫沉淀（IP）