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Phospho-mTOR (Ser2448) monoclonal antibody

货号: MB11248

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11248

Product Name :Phospho-mTOR (Ser2448) monoclonal antibody

Swiss-Prot :P42345

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 289 kDa; Observed MW: 289 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-mTOR in Hela, Hela+EGF lysates using Phospho-mTOR antibody.

Western blot analysis of mTOR in 3t3 lysates using mTOR antibody.