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Phospho-MSK1 (Ser376) monoclonal antibody

货号: MB11239

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11239

Product Name :Phospho-MSK1 (Ser376) monoclonal antibody

Swiss-Prot :O75582

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 90 kDa; Observed MW: 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Ser376 of human MSK1

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-MSK1 in rat brain lysates using Phospho-MSK1 antibody.

Western blot analysis of Phospho-MSK1 in K562 lysates using Phospho-MSK1 antibody.