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LC3A monoclonal antibody

货号: MB11186

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11186

Product Name :LC3A monoclonal antibody

Swiss-Prot :Q9H492

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3), and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 14 kDa; Observed MW: 14,16 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha

Immunogen :A synthetic peptide of human MAP1LC3A

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LC3A in 3T3, mouse heart, mouse brain lysates using LC3A antibody.

Western blot analysis of LC3A in K562, rat Brain, Hela lysates using LC3A antibody.