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LXR alpha monoclonal antibody

货号: MB11179

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11179

Product Name :LXR alpha monoclonal antibody

Swiss-Prot :Q13133

Host :Rabbit

Reactivity :Human,Rat

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 50 kDa; Observed MW: 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NR1H3; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3

Immunogen :A synthetic peptide of human LXR alpha

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LXR alpha in Jurkat lysates using LXR alpha antibody.

Western blot analysis of LXR alpha in rat Brain lysates using LXR alpha antibody.