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KDM4B monoclonal antibody

货号: MB11144

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11144

Product Name :KDM4B monoclonal antibody

Swiss-Prot :O94953

Host :Rabbit

Reactivity :Human

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 122 kDa; Observed MW: 150 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B

Immunogen :A synthetic peptide of human KDM4B/JMJD2B

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of KDM4B in 293, COS7 lysates using KDM4B antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KDM4B/JMJD2B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.