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kappa Opioid Receptor monoclonal antibody

货号: MB11138

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11138

Product Name :kappa Opioid Receptor monoclonal antibody

Swiss-Prot :P33534

Host :Rabbit

Reactivity :Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 43 kDa; Observed MW: 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KOR; R21; KOR-1; MSL-1; Oprk2; K-OR-1

Immunogen :A synthetic peptide of mouse Kappa Opioid Receptor

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Kappa Opioid Receptor in rat Brain lysates using kappa Opioid Receptor antibody.

免疫沉淀（IP）