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Phospho-IGF1 Receptor (Tyr1166) monoclonal antibody

货号: MB11111

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11111

Product Name :Phospho-IGF1 Receptor (Tyr1166) monoclonal antibody

Swiss-Prot :P08069

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 155 kDa; Observed MW: 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-IGF1R in C6, 3T3, Hela lysates using Phospho-IGF1 Receptor antibody.

免疫沉淀（IP）