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HP1 alpha monoclonal antibody

货号: MB11056

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB11056

Product Name :HP1 alpha monoclonal antibody

Swiss-Prot :P45973

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background :Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 22 kDa; Observed MW: 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha

Immunogen :A synthetic peptide of human HP1 alpha

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HP1 alpha in C6, PC-12 lysates using HP1 alpha antibody.

Western blot analysis of HP1 alpha in 3T3, Hela lysates using HP1 alpha antibody.