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HOPX monoclonal antibody

货号: MB11054

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB11054

Product Name :HOPX monoclonal antibody

Swiss-Prot :Q8R1H0

Host :Rabbit

Reactivity :Human

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (PubMed:12297045, PubMed:12297046). Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding .

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 8 kDa; Observed MW: 12 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Hod; Hop; Ob1; Obl; Hdop; Toto; Cameo; AI848177; AW490897; 1110018K11Rik; 1200015P04Rik; 2300002F06Rik

Immunogen :Recombinant protein of mouse HOPX

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of HOPX/HOD in Hela lysates using HOPX antibody.

免疫沉淀（IP）