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FADD monoclonal antibody

货号: MB10902

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10902

Product Name :FADD monoclonal antibody

Swiss-Prot :Q61160

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 23 kDa; Observed MW: 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mort1/FADD

Immunogen :A synthetic peptide of mouse FADD

Conjugate :Unconjugated

Modification :Unmodified

Immunohistochemistry analysis of paraffin-embedded mouse liver using FADD antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of FADD in Raw264.7 lysates using FADD antibody.