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EMAP II monoclonal antibody

货号: MB10875

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10875

Product Name :EMAP II monoclonal antibody

Swiss-Prot :Q12904

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1/500-1/1000

Background :Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 34 kDa; Observed MW: 34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :p43; HLD3; EMAP2; SCYE1; EMAPII; AIMP1

Immunogen :A synthetic peptide of human EMAP II

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of EMAP II/AIMP1 in HT-1080 lysates using EMAP II antibody.

免疫沉淀（IP）