产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

4E BP1 monoclonal antibody

货号: MB10871

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10871

Product Name :4E BP1 monoclonal antibody

Swiss-Prot :Q13541

Host :Rabbit

Reactivity :Human,Mouse,Rat,Hamster

Applications :WB,IHC-P,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background :Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 13 kDa; Observed MW: 15-20 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

Immunogen :A synthetic peptide of human eIF4EBP1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of eIF4EBP1 in mouse heart lysates using 4E BP1 antibody.

Western blot analysis of eIF4EBP1 in Jurkat, C6, CHO-K1 lysates using eIF4EBP1 antibody.