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DGCR8 monoclonal antibody

货号: MB10830

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10830

Product Name :DGCR8 monoclonal antibody

Swiss-Prot :Q8WYQ5

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 86 kDa; Observed MW: 120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DGCR8; DGCRK6; Gy1; C22orf12; D16Wis2; pasha

Immunogen :Recombinant protein of human DGCR8

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of DGCR8 in K562 using DGCR8 antibody,and DAPI.

免疫沉淀（IP）