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CRM1 monoclonal antibody

货号: MB10766

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10766

Product Name :CRM1 monoclonal antibody

Swiss-Prot :O14980

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background :Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 123 kDa; Observed MW: 123 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog

Immunogen :A synthetic peptide of human CRM1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CRM1 in 3T3 lysates using CRM1 antibody.

免疫沉淀（IP）