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CIP4 monoclonal antibody

货号: MB10738

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10738

Product Name :CIP4 monoclonal antibody

Swiss-Prot :Q15642

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC-P

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100

Background :Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling . Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 68 kDa; Observed MW: 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :STP; CIP4; HSTP; STOT; TRIP-10

Immunogen :A synthetic peptide of human Cip4

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Cip4 in 3T3 lysates using CIP4 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Cip4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.