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Caspase 11 monoclonal antibody

货号: MB10660

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10660

Product Name :Caspase 11 monoclonal antibody

Swiss-Prot :P70343

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 43 kDa; Observed MW: 43,38,25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Caspl; ich-3; CASP-4; Casp11; CASP-11

Immunogen :Recombinant protein of mouse Caspase-11

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Caspase11 in C6, 3T3, Hela lysates using Caspase 11 antibody.

免疫沉淀（IP）