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BMP4 monoclonal antibody

货号: MB10628

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10628

Product Name :BMP4 monoclonal antibody

Swiss-Prot :P12644

Host :Rabbit

Reactivity :Human

Applications :WB,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background :Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation. BMPs belongs to the TGF-β superfamily, playing many diverse functions during development. BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 47 kDa; Observed MW: 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BMP4; BMP2B; DVR4; Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B

Immunogen :A synthetic peptide of human BMP4

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of BMP4 in HEPG2 using BMP4 antibody,and DAPI.

免疫沉淀（IP）