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ATP6V0D1 monoclonal antibody

货号: MB10594

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB10594

Product Name :ATP6V0D1 monoclonal antibody

Swiss-Prot :P61421

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC-F,IHC-P,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background :Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis . May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 40 kDa; Observed MW: 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD

Immunogen :Recombinant protein of human ATP6V0D1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of ATP6V0D1 in K562, rat Brain, C6, 3T3, Hela lysates using ATP6V0D1 antibody.

Immunocytochemistry analysis of ATP6V0D1 in Hela using ATP6V0D1 antibody,and DAPI