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Phospho-ATP Citrate Synthase (Thr447/Ser451) monoclonal antibody

货号: MB10589

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10589

Product Name :Phospho-ATP Citrate Synthase (Thr447/Ser451) monoclonal antibody

Swiss-Prot :P53396

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1/500-1/1000

Background :ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 121 kDa; Observed MW: 121 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Immunogen :A synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ATP citrate lyase

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of Phospho-ATP citrate lyase in K562 lysates using Phospho-ATP Citrate Synthase antibody.

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