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ATM monoclonal antibody

货号: MB10588

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10588

Product Name :ATM monoclonal antibody

Swiss-Prot :Q13315

Host :Rabbit

Reactivity :Human

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 351 kDa; Observed MW: 351 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated

Immunogen :Recombinant protein of ATM

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of ATM in Hela lysates using ATM antibody.

免疫沉淀（IP）