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Aprataxin monoclonal antibody

货号: MB10561

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :MB10561

Product Name :Aprataxin monoclonal antibody

Swiss-Prot :Q7Z2E3

Host :Rabbit

Reactivity :Human

Applications :WB,ICC/IF

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200

Background :DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) .

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 41 kDa; Observed MW: 41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT

Immunogen :A synthetic peptide of human Aprataxin

Conjugate :Unconjugated

Modification :Unmodified

Immunocytochemistry analysis of Aprataxin in U87-MG using Aprataxin antibody,and DAPI.

免疫沉淀（IP）