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APPBP1 monoclonal antibody

货号: MB10559

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB10559

Product Name :APPBP1 monoclonal antibody

Swiss-Prot :Q13564

Host :Rabbit

Reactivity :Human

Applications :WB,IP

Application_all :WB: 1/500-1/1000 IP: 1/20

Background :Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.

Product :50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 60 kDa; Observed MW: 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NEDD8 activating enzyme E1 subunit 1; HPP1; ula-1; APPBP1; A-116A10.1

Immunogen :A synthetic peptide of human APPBP1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of APPBP1 in SKOV-3 lysates using APPBP1 antibody.

免疫沉淀（IP）